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  Clinical Pulmonary Infection Score (CPIS)

 
Patient temperature

≥36.5 degrees C and ≤38.4 degrees C (0 points)

≥38.5 degrees C and ≤38.9 degrees C (1 point)

≥39 degrees C (2 points)

≤36 degrees C (2 points)
WBC

≥4,000/mm-3 and ≤11,000/mm-3 (0 points)

<4,000/mm-3 or >11,000/mm-3 (1 point)

<4,000/mm-3 or >11,000/mm-3 with ≥500 bands (2 points)
Tracheal secretions (0-4+ quantifications summed over 24 hours)

<14+ (0 points)

≥14+ (1 point)

≥14+ and purulent (2 points)
PaO2(mmHg)/FIO2

>240 or ARDS present (0 points)

≤240 or no ARDS present (2 points)
Chest X-Ray

No infiltrate (0 points)

Patchy or diffuse infiltrate (1 point)

Distinct infiltrate (2 points)
Quantitative pathogenic bacterial culture growth from tracheal aspirate

≤1+ or no growth (0 points)

>1+ (1 point)

>1+ and same bacteria seen on gram stain (2 points)

 
Important: Inputs must be complete to perform calculation.

 
Total Criteria Point Count:
 
     
 
Include literature references: Yes   No

 
  CPIS Interpretation

 
0 to 6 points: Pneumonia less likely
7 to 12 points: Pneumonia more likely

 
Notes
  • The CPIS is used in the diagnosis of ventilator associated pneumonia.

 
References
  1. Pugin J, Auckenthaler R, Mili N, et al. Diagnosis of ventilator-associated pneumonia by bacteriologic analysis of bronchoscopic and nonbronchoscopic "blind" bronchoalveolar lavage fluid. Am Rev Respir Dis. 1991 May;143(5 Pt 1):1121-9. PubMed ID: 2024824 PubMed Logo
  2. Rosbolt MB, Sterling ES, Fahy BG. The utility of the clinical pulmonary infection score. J Intensive Care Med. 2009 Jan-Feb;24(1):26-34. doi: 10.1177/0885066608327097. Epub 2008 Nov 19. Review. PubMed ID: 19019839 PubMed Logo
  3. Singh N, Rogers P, Atwood CW, et al. Short-course empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit. A proposed solution for indiscriminate antibiotic prescription. Am J Respir Crit Care Med. 2000 Aug;162(2 Pt 1):505-11. PubMed ID: 10934078 PubMed Logo

 

 
Associated ICD10-CM Codes
 
   I27.82Chronic pulmonary embolism
   I50.9Heart failure, unspecified
   J18.0Bronchopneumonia, unspecified organism

 
Associated ICD9-CM Codes
 
   482.9Bacterial pneumonia nos
   485Bronchopneumonia org nos
   481Pneumococcal pneumonia
   480.9Viral pneumonia nos

 

 
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All information contained in and produced by the EBMcalc system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. Click here for full notice and disclaimer.
 
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