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  Cardiovascular Risk Assessment (10-year, MESA 2015, with or without CAC score)

 
Terms = (Age * 0.0455) + (Sex * 0.7496) + ((Race == 1?1:0) * -0.2111) + ((Race == 2?1:0) * -0.5055) + ((Race == 3?1:0) * -0.19) + (Diabetes * 0.5168) + (Smoker * 0.4732) + (Totalcholesterol * 0.0053) - (HDLcholesterol * 0.0140) + (On lipid-lowering medication * 0.2473) + (Systolic blood pressure * 0.0085) + (On hypertension medication * 0.3381) + (Family history of MI * 0.4522)
10-year risk = 100 * (1 - 0.99963e(Terms))
Terms CAC = (Age * 0.0172) + (Sex * 0.4079) + ((Race == 1?1:0) * 0.0353) + ((Race == 2?1:0) * -0.3475) + ((Race == 3?1:0) * -0.0222) + (Diabetes * 0.3892) + (Smoker * 0.3717) + (Totalcholesterol * 0.0043) - (HDLcholesterol * 0.0114) + (On lipid-lowering medication * 0.1206) + (Systolic blood pressure * 0.0066) + (On hypertension medication * 0.2278) + (Family history of MI * 0.3239) + (ln(CAC + 1) * 0.2743)
10-year risk CAC = 100 * (1 - 0.99833e(Terms CAC))

 
Input:
 
Race African American

Chinese American

Hispanic

Non-Hispanic white
Sex Female

Male
Age  
Total cholesterol  
HDL cholesterol  
Systolic blood pressure  
On hypertension medication No

Yes
On lipid-lowering medication No

Yes
Diabetes No

Yes
Smoker No

Yes
Family history of MI No

Yes
CAC   Agatston units
Results:
 
Terms  
10-year risk  
Terms CAC  
10-year risk CAC  
 
Decimal Precision  

 
     
 

 
Notes

 
Related Results
 
          
 

 
References
  1. Smith DA. ACP Journal Club. In adults without CVD, the MESA score, including coronary artery calcium, predicted 10-y risk for CHD events. Ann Intern Med. 2016 Mar 15;164(6):JC35. PMID: 26974735 PubMed Logo
  2. McClelland RL, Jorgensen NW, Budoff M, et. al. 10-Year Coronary Heart Disease Risk Prediction Using Coronary Artery Calcium and Traditional Risk Factors: Derivation in the MESA (Multi-Ethnic Study of Atherosclerosis) With Validation in the HNR (Heinz Nixdorf Recall) Study and the DHS (Dallas Heart Study). J Am Coll Cardiol. 2015 Oct 13;66(15):1643-53. PMID: 26449133 PubMed Logo

 
Associated Medical Subject Headings [MeSH] Terms
 
         80 and over,   Aged,   Atherosclerosis,   Calcinosis,   Coronary Angiography,   Coronary Artery Disease,   Coronary Vessels,   Ethnic Groups,   Female,   Follow-Up Studies,   Humans,   Male,   Middle Aged,   Prospective Studies,   Reproducibility of Results,   Risk Assessment,   Risk Factors,   Tomography,   X-Ray Computed

 
Associated Logical Observation Identifiers Names and Codes [LOINC]
 
Parameter LOINC's and Units
Age 21612-7 : Years old      21612-7 : yr      21612-7 : years      30525-0 : Years old      30525-0 : yr      30525-0 : years      
Total Cholesterol 2093-3 : mg/dL      14647-2 : mmol/L      
HDL Cholesterol 2085-9 : mg/dL      14646-4 : mmol/L      
Systolic Blood Pressure 8480-6 : mmHg      

 
This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, and LOINC panels and forms file are copyright © 1995-2014, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and available at no cost under the license at http://loinc.org/terms-of-use.

 
Associated ICD10-CM Codes
 
   I25.84Coronary atherosclerosis due to calcified coronary lesion
   E78.5Hyperlipidemia, unspecified
   E78.4Other hyperlipidemia
   E78.2Mixed hyperlipidemia
   I10Essential (primary) hypertension
   I67.2Cerebral atherosclerosis

 
Associated ICD9-CM Codes
 
   434.0Cerebral thrombosis
   437.0Cerebral atherosclerosis
   401Essential hypertension
   401.1Benign hypertension
   272.2Mixed hyperlipidemia
   272.4Hyperlipidemia nec/nos
   414.0Coronary atherosclerosis
   414.4Coronary atherosclerosis

 
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