EBMcalc Logo
  Gail Model for 5 Year Risk of Breast Cancer (1999 paper)

RelativeRisk = AgeMenarche * NumBiops * AgeFLBNumRels * AtypHyper
FiveYearRisk = RelativeRisk * BaselineAgeRace

Age Menarche Age at menarche >=14 years old (1.00)

12-13 years old (1.10)

<12 years old (1.21)
Num Biops
Age FLB Num Rels
Atyp Hyper No biopsies (1.00)

At least one biopsy and no atypical hyperplasia found in any biopsy specimen (0.93)

No atypical hyperplasia found and hyperplasia status unknown for at least one biopsy specimen (1.00)

Atypical hyperplasia found in at least one biopsy specimen (1.82)
Baseline Age Race
Relative Risk  
Five Year Risk  
Decimal Precision  

Include literature references: Yes   No

Related Results

  1. Gail MH, Constantino JP, Bryant J, et al. Weighing the Risks and Benefits of Tamoxifen Treatment for Preventing Breast Cancer. J. National Cancer Institute. 1999; V91, #21, pages 1829-1846. PubMed ID: 10547390 PubMed Logo
  2. Costantino JP, Gail MH, Pee D, et al. Validation studies for models projecting the risk of invasive and total breast cancer incidence. J Natl Cancer Inst. 1999 Sep 15;91(18):1541-8. PubMed ID: 10491430 PubMed Logo
  3. EBMcalc CrossRef: Gail Model (1989 paper)
  4. EBMcalc CrossRef: Odds Ratio and Relative Risk
  5. EBMcalc CrossRef: Breast Cancer Local Recurrence Risk

Associated Medical Subject Headings [MeSH]
         Age Factors,   Aged,   Anticarcinogenic Agents,   Bone,   Breast Neoplasms,   Carcinoma in Situ,   Cataract,   Controlled Clinical Trials as Topic,   Counseling,   Education,   Endometrial Neoplasms,   Estrogen Receptor Modulators,   Female,   Fractures,   Humans,   Incidence,   Logistic Models,   Mammography,   Mass Screening,   Middle Aged,   Models,   National Institutes of Health (U.S.),   Neoplasm Invasiveness,   Patient Education as Topic,   Pulmonary Embolism,   Reproducibility of Results,   Risk,   Risk Factors,   Selective Estrogen Receptor Modulators,   Statistical,   Stroke,   Tamoxifen,   Venous Thrombosis

Associated ICD10-CM Codes
   C50.919Malignant neoplasm of unspecified site of unspecified female breast
   C50.819Malignant neoplasm of overlapping sites of unspecified female breast
   N63Unspecified lump in breast
   Z85.3Personal history of malignant neoplasm of breast
   D49.3Neoplasm of unspecified behavior of breast

Associated ICD9-CM Codes
   239.3Breast neoplasm nos
   V10.3Hx of breast malignancy
   611.72Lump or mass in breast
   174.8Malign neopl breast nec
   174.9Malign neopl breast nos

Legal Notices and Disclaimer

All information contained in and produced by the EBMcalc system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. Click here for full notice and disclaimer.
EBMcalc is Copyright © 1998-2019 Foundation Internet    [Build 256169 v19.1]