SIRS Criteria: Systemic Inflammatory Response Syndrome

 

Input
 

Temperature		degC degF
Pulse		beats/min bpm
Respiratory Rate		br/min breaths/min
PaCO2		Pascal atm bar cmH2O cmHg ftH2O gm/sqcm inH2O inHg kPa mbar mmHg psi torr
WBC		#/mcL #/microL / nl /mcL /microL 10E+9/L 10^3/microL Mill/mcl Thous/mcL X10E+09/L X10E+12/L cells/mcL cells/microL m/cmm x10(12)/L x10(3)/mcL x10(3)/microL x10(6)/L x10(6)/mcL x10(6)/microL x10(9)/L x1000/mm3 x10^12/L x10^3/mcL x10^3/microL x10^6/L x10^6/mcL x10^6/microL x10^9/L
WBC Band Percent		% fraction percent rate ratio

 
Results
 

SIRS Score		# index logit none number points score

 

   
 
Include literature references: Yes   No

 

SIRS interpretation

 

0 to 1 point:	SIRS not present
2 to 4 points:	SIRS present

 

 

 
Equations used
 

SIRSScore = TempFactor + PulseFactor + WBCFactor + RespFactor

 

 

Calculation Details and Variables

• TempFactor is assigned values by this ordered logic:
  • If Temperature >38 degC TempFactor = 1
  • Else if Temperature ≥36 degC TempFactor = 0
  • Else TempFactor = 1.
• PulseFactor is assigned values by this ordered logic:
  • If Pulse >90 beats/min PulseFactor = 1
  • Else PulseFactor = 0.
• The RespFactor is set to 1 when the RespiratoryRate is >20 breaths/min or the PaCO₂ is <20 mmHg. Otherwise the RespFactor is set to 0.
• The WBCFactor is set to 1 if the WBC is <4,000 #/microL, the WBC >12,000 #/microL, or the WBCBandPercent is >10%. Otherwise the WBCFactor is dset to 0.

 

References

1. Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest. 1992 Jun;101(6):1644-55. PubMed ID: 1303622

 

Associated Medical Subject Headings [MeSH]
 

Critical Care, Humans, Medical, Multiple Organ Failure, Pulmonary Medicine, Sepsis, Septic, Severity of Illness Index, Shock, Societies, Syndrome, Terminology as Topic

 

Associated Logical Observation Identifiers Names and Codes [LOINC]
 

Parameter	LOINC's and Suggested Units
Temperature	8329-5 : degC      8310-5 : degC      8331-1 : degC      8332-9 : degC      8333-7 : degC      8328-7 : degC
Pulse	8867-4 : beats/min      8893-0 : beats/min      8890-6 : beats/min      8889-8 : beats/min      68999-2 : beats/min      76282-3 : beats/min      69000-8 : beats/min
Respiratory Rate	9303-9 : breaths/min      9279-1 : breaths/min      76170-0 : breaths/min      19840-8 : breaths/min
PaCO2	2019-8 : mmHg      34705-4 : mmHg
WBC	6690-2 : #/microL
WBC Band Percent	764-1 : %      35332-6 : %      26508-2 : %

 
This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, and LOINC panels and forms file are copyright © 1995-2014, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and available at no cost under the license at http://loinc.org/terms-of-use.