This calculator evaluates the following Clinical Criteria:
- Sex
- Alkaline phosphatase / aminotransferase ratio
- Ratio of serum globulin, gamma globulin or IgG to corresponding normal
- Autoantibodies (titres by immunofluorescence on rodent tissues)
- Positive antimitochondrial antibody
- Viral markers
- History of recent hepatotoxic drug exposure or parenteral exposure to blood products
- Alcohol consumption
- Other autoimmune diseases in patient or first-degree relatives
- HLA B8-DR3 haplotype or DR4 allotype
- Histology
- Response to therapy
References
- Johnson PJ, MacFarland IG. Meeting report: International autoimmune hepatitis group. Hepatology. 1993;18:998-1005. PubMed ID: 8406375
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