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COVID-19 Critical Illness Predictor (Liang 5/12/2020)

 

Input
 

Age		mo yr
LDH		IU/L IntUnit/L U/L Unit/L Units/L mcKat/L
Absolute Neutrophil Count		#/mcL #/microL / nl /mcL /microL 10*3/uL 10*6/uL 10*6/uL 10E+9/L 10^3/microL K/mm3 K/uL Mill/mcl Million/ul Thous/mcL Thousand/uL X10E+09/L X10E+12/L cells/mcL cells/microL m/cmm thou/mcL x10(12)/L x10(3)/mcL x10(3)/microL x10(6)/L x10(6)/mcL x10(6)/microL x10(9)/L x1000/mm3 x10^12/L x10^3/mcL x10^3/microL x10^6/L x10^6/mcL x10^6/microL x10^9/L {cells}/uL
Absolute Lymphocyte Count		#/mcL #/microL / nl /mcL /microL 10*3/uL 10*6/uL 10*6/uL 10E+9/L 10^3/microL K/mm3 K/uL Mill/mcl Million/ul Thous/mcL Thousand/uL X10E+09/L X10E+12/L cells/mcL cells/microL m/cmm thou/mcL x10(12)/L x10(3)/mcL x10(3)/microL x10(6)/L x10(6)/mcL x10(6)/microL x10(9)/L x1000/mm3 x10^12/L x10^3/mcL x10^3/microL x10^6/L x10^6/mcL x10^6/microL x10^9/L {cells}/uL
Direct Bilirubin		mcmol/L mg% mg/dL
Comorbidities		# count index logit none number points score
Abnormal Chest X-ray	(1.2205)
Hemoptysis	(1.5116)
Dyspnea	(0.632)
Unconscious	(1.5494)
Presence of Cancer	(1.4037)

 
Results
 
Important: Inputs must be complete to perform calculation.

 

Factors		# count index logit none number points score
Critical Illness Probability		% fraction percent rate ratio
Decimal Precision   0 1 2 3

 

     
 
Include literature references: Yes   No

 

 

Notes

• This calculator represents findings from the literature referenced below. It is important to understand that these findings may not be representative of the experience in your local healthcare system.
• Comorbidities includes COPD, hypertention, diabetes, coronary disease, kidney disease, cancer, cerebrovascular disease, hepatitis B and immunodeficiency.

 
Equations used
 

Factors = (Age * 0.0276) + (LDH * 0.0024) + (0.0562 * AbsoluteNeutrophilCount / AbsoluteLymphocyteCount) + (DirectBilirubin * 0.1376) + (Comorbidities * 0.4668) + CXR + Hemoptysis + Dyspnea + Unconscious + Cancer - 6.6127

CriticalIllnessProbability = 100 * e(Factors) / (1 + e(Factors))

 

 

References

1. Liang W, Liang H, Ou L, et al. Development and Validation of a Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19. JAMA Intern Med. 2020 May 12. PubMed ID: 32396163

 

Associated Medical Subject Headings [MeSH]
 

Adult,   Aged,   Betacoronavirus,   Clinical Laboratory Techniques,   Cohort Studies,   Coronavirus Infections,   Critical Care,   Critical Illness,   Female,   Hospitalization,   Humans,   Male,   Middle Aged,   Pandemics,   Pneumonia,   Risk Assessment,   Viral

 

Associated Logical Observation Identifiers Names and Codes [LOINC]
 

Parameter	LOINC's and Suggested Units
Age	21612-7 : yr      21612-7 : yr      21612-7 : years      30525-0 : Years old      30525-0 : yr      30525-0 : years
LDH	14804-9 : U/L      14805-6 : U/L      2537-9 : U/L
Absolute Neutrophil Count	751-8 : 10^3/microL      26499-4 : 10^3/microL      753-4 : 10^3/microL
Absolute Lymphocyte Count	731-0 : x10^3/microL      26474-7 : x10^3/microL      732-8 : x10^3/microL
Direct Bilirubin	1968-7 : mg/dL      14629-0 : mcmol/L

 
This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, and LOINC panels and forms file are copyright © 1995-2014, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and available at no cost under the license at http://loinc.org/terms-of-use.