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  COVID-19 Symptom-Based C19 Rule for Diagnosis

 
Symptoms

Loss of taste or smell (2 points)

Cough and fever (1 point)

Chest tightness or wheezing (-1 point)

 
Important: Inputs must be complete to perform calculation.

 
Total Criteria Point Count:
 
     
 
Include literature references: Yes   No

 
  C19 Rule Interpretation

 
3 points: LR+ 15 for diagnosis of COVID-19
2 points: LR+ 4.2 for diagnosis of COVID-19
1 point: LR+ 1.2 for diagnosis of COVID-19
0 points: LR+ 0.7 for diagnosis of COVID-19
-1 points: LR+ 0.1 for diagnosis of COVID-19

 
Notes
  • When the odds (by prevalence) of COVID-19 is known, these odds may be mutiplied by the calculated LR+ to obtain the post-test odds of COVID-19 in individuals with the symptoms above.
  • LR+: likelyhood ratio of a positive test.

 
References
  1. Smith DS, Richey EA, Brunetto WL. A Symptom-Based Rule for Diagnosis of COVID-19. SN Compr Clin Med. 2020 Oct 24:1-8. PubMed ID: 33134843 PubMed Logo

 

 
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