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COVID-19 CALL Score

 

Input
 

Comorbidity	No (1)
	Yes (4)
Age		mo yr
Absolute Lymphocyte Count		#/mcL #/microL / nl /mcL /microL /uL 10*3/uL 10*6/uL 10*6/uL 10E+9/L 10^3/microL K/mm3 K/uL Mill/mcl Million/ul Thous/mcL Thousand/uL X10E+09/L X10E+12/L cells/mcL cells/microL m/cmm thou/mcL x10(12)/L x10(3)/mcL x10(3)/microL x10(6)/L x10(6)/mcL x10(6)/microL x10(9)/L x1000/mm3 x10^12/L x10^3/mcL x10^3/microL x10^6/L x10^6/mcL x10^6/microL x10^9/L {cells}/uL
LDH		IU/L IntUnit/L U/L Unit/L Units/L mcKat/L

 
Result
 
Important: Inputs must be complete to perform calculation.

 

CALL Score		# count index logit none number points score

 

CALL Score Interpretation

 

4 to 6 points:	Low risk of disease progression
7 to 13 points:	High risk of disease progression

 

 

Data action

 
     
 
Include literature references: Yes   No

 

 

Notes

• This calculator represents findings from the literature referenced below. It is important to understand that these findings may not be representative of the experience in your local healthcare system.
• CALL: Comorbidity, Age, Lymphocyte, and LDH.
• Comorbidities include HIV, Chronic lung disease, cardiovascular disease, diabetes, and hypertension.
• The follow-up study in Turkey^[2] showed less predictive power (ROC-AUC 0.59) than the original Chinese study (ROC-AUC 0.91).^[1]

 
Equations used
 

CALLScore = Comorbidity + AgeFactor + LymphocyteFactor + LDHFactor

 

 

Calculation Details and Variables

• Equation parameters such as Comorbidity, have two or more discrete values that may be used in the calculation. The numbers in the parentheses, e.g. (1), represent the values that will be used.
• AgeFactor is assigned values by this ordered logic:
  • If Age >60 yr, AgeFactor = 3
  • Else AgeFactor = 1.
• LymphocyteFactor is assigned values by this ordered logic:
  • If Absolute Lymphocyte Count ≤1 x10(9)/L, LymphocyteFactor = 3
  • Else LymphocyteFactor = 1.
• LDHFactor is assigned values by this ordered logic:
  • If LDH >500 U/L, LDHFactor = 3
  • Else if LDH ≥250 U/L, LDHFactor = 2
  • Else LDHFactor = 1.

 

References

1. Ji D, Zhang D, Xu J, et al. Prediction for Progression Risk in Patients With COVID-19 Pneumonia: The CALL Score. Clin Infect Dis. 2020 Sep 12;71(6):1393-1399. PubMed ID: 32271369
2. Erturk Sengel B, Tukenmez Tigen E, Ilgin C, et al. Application of CALL score for prediction of progression risk in patients with COVID-19 at university hospital in Turkey. Int J Clin Pract. 2021 Jul 26:e14642. PubMed ID: 34310000

 

Associated Medical Subject Headings [MeSH]
 

Adult,   Aged,   Betacoronavirus,   COVID-19,   China,   Clinical Decision Rules,   Coronavirus Infections,   Disease Progression,   Female,   Hospitals,   Humans,   Lymphocyte Count,   Male,   Middle Aged,   Multivariate Analysis,   Nomograms,   Pandemics,   Pneumonia,   Prognosis,   Proportional Hazards Models,   Retrospective Studies,   Risk Assessment,   Risk Factors,   SARS-CoV-2,   Severity of Illness Index,   Turkey,   University,   Viral

 

Associated Logical Observation Identifiers Names and Codes [LOINC]
 

Parameter	LOINC's and Suggested Units
Age	21612-7 : yr      21612-7 : yr      21612-7 : years      30525-0 : Years old      30525-0 : yr      30525-0 : years
Absolute Lymphocyte Count	731-0 : x10^3/microL      26474-7 : x10^3/microL      732-8 : x10^3/microL
LDH	14804-9 : U/L      14805-6 : U/L      2537-9 : U/L

 
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