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COVID-19 and the Prognostic Nutrition Index (PNI)

 

Input
 

Albumin		g/L g/dL gm/L gm/dL mcg/dL mcg/mL mg% mg/dL mg/mL ng/mL
Absolute Lymphocyte Count		#/mcL #/microL / nl /mcL /microL /uL 10*3/uL 10*6/uL 10*6/uL 10E+9/L 10^3/microL K/mm3 K/uL Mill/mcl Million/ul Thous/mcL Thousand/uL X10E+09/L X10E+12/L cells/mcL cells/microL m/cmm thou/mcL x10(12)/L x10(3)/mcL x10(3)/microL x10(6)/L x10(6)/mcL x10(6)/microL x10(9)/L x1000/mm3 x10^12/L x10^3/mcL x10^3/microL x10^6/L x10^6/mcL x10^6/microL x10^9/L {cells}/uL

 
Result
 
Important: Inputs must be complete to perform calculation.

 

PNI		# count index logit none number points score
Decimal Precision   0 1 2 3

 

PNI Interpretation

 

PNI <43.7:	In-hospital mortality odds ratio 12.2
PNI >=43.7 and <=51.4:	In-hospital mortality odds ratio 1.5
PNI >51.4:	In-hospital mortality odds ratio 1 (index)

 

 

Data action

 
     
 
Include literature references: Yes   No

 

 

Notes

• In this calculator, mcg is the abbreviation for micrograms.
• This calculator represents findings from the literature referenced below. It is important to understand that these findings may not be representative of the experience in your local healthcare system.
• In-hospital mortality odds ratios were adjusted for covariates.^[2]
• PNI cutoffs predicting in-hospital motalty rage from 36.85 (sensitivity 70.29%, specificity 69.23%)^[3] to 42.1 (sensitivity 81.8%, specificity 72%).^[2]

 
Equations used
 

PNI = (10 * Albumin) + (0.005 * AbsoluteLymphocyteCount)

 

 

References

1. Onodera T, Goseki N, Kosaki G. Prognostic nutritional index in gastrointestinal surgery of malnourished cancer patients. Nihon Geka Gakkai Zasshi. 1984 Sep;85(9):1001-5. Japanese. PubMed ID: 6438478
2. Cınar T, Hayıroglu Mİ, Cicek V, et al. Is prognostic nutritional index a predictive marker for estimating all-cause in-hospital mortality in COVID-19 patients with cardiovascular risk factors? Heart Lung. 2021 Mar-Apr;50(2):307-312. PubMed ID: 33482433
3. Rashedi S, Keykhaei M, Pazoki M, et al. Clinical significance of prognostic nutrition index in hospitalized patients with COVID-19: Results from single-center experience with systematic review and meta-analysis. Nutr Clin Pract. 2021 Jul 16. PubMed ID: 34270114

 

Associated Medical Subject Headings [MeSH]
 

COVID-19,   Cardiovascular Diseases,   Cross-Sectional Studies,   Digestive System Neoplasms,   Heart Disease Risk Factors,   Hospital Mortality,   Humans,   Nutrition Assessment,   Nutritional Physiological Phenomena,   Nutritional Status,   Parenteral Nutrition,   Prognosis,   Retrospective Studies,   Risk,   Risk Factors,   SARS-CoV-2,   Total

 

Associated Logical Observation Identifiers Names and Codes [LOINC]
 

Parameter	LOINC's and Suggested Units
Albumin	1751-7 : g/dL
Absolute Lymphocyte Count	731-0 : x10^3/microL      26474-7 : x10^3/microL      732-8 : x10^3/microL

 
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