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Risk of Acquiring Diabetes Mellitus (7.5-year) and Optimization

 

Input
 

Age		mo yr
Height		cm inch in mm m
Weight		gm kg lb
Sex	Female (1)
	Male (0)
MA	Mexican American (1)
	Non-Hispanic white (0)
FMH DM	No family history of DM (0)
	Positive family history of DM (1)
FBS		mg/dL mmol/L
Systolic Blood Pressure		Pascal cmH2O mmHg mm[Hg] torr
HDL Cholesterol		mg/dL mmol/L

 
Results
 
Important: Inputs must be complete to perform calculation.

 

BMI		kg/m(2) kg/m(2) kg/m2 kg/m2 kg/m^2 kg/m^2 kg/sqm
Terms		# count index logit none number points score
Risk of Diabetes		% fraction percent rate ratio
Decimal Precision   0 1 2 3

 

Data action

 
    Difficulty:   Easy Difficulty:   Medium Difficulty:   Hard

 

 

 

Notes

• BMI is body mass index.
• FBS is fasting blood sugar.
• A FMH DM means at least one parent or sibling has diabetes.
• Optimization limits include: HDL Cholesterol ≤150 mg/dL. Systolic Blood Pressure must be ≥95 mmHg. Minimal BMI is 20 kg/m² and minimal FBS is 60 mg/dl.
• Easy optimizations include:
   
  1) Decrease weight 5%  
  2) Decrease FBS 10%  
  3) Decrease systolic blood pressure 10%  
  4) Increase HDL cholesterol 10%
• Medium intensity optimizations include:
   
  1) Decrease weight 10%  
  2) Decrease FBS 25%  
  3) Decrease systolic blood pressure 20%  
  4) Increase HDL cholesterol 20%
• Hard optimizations include:
   
  1) Decrease weight 20%  
  2) Decrease FBS 50%  
  3) Decrease systolic blood pressure 30%  
  4) Increase HDL cholesterol 30%

 
Equations used
 

BMI = (Weight/2.205) / (Height/39.37)2

Terms = (0.028 * Age) + (0.661 * Sex) + (0.412 * MA) + (0.079 * FBS) + (0.018 * SystolicBloodPressure) - (0.039 * HDLCholesterol) + (0.07 * BMI) + (0.481 * FMHDM) - 13.415

RiskofDiabetes = 100 / (1 + e(-1*Terms))

 

 

Calculation Details and Variables

• Equation parameters such as Sex, have two or more discrete values that may be used in the calculation. The numbers in the parentheses, e.g. (1), represent the values that will be used.

 

References

1. Stern MP, Williams K, Haffner SM. Identification of persons at high risk for type 2 diabetes mellitus: do we need the oral glucose tolerance test? Ann Intern Med. 2002 Apr 16;136(8):575-81. PubMed ID: 11955025

 

Associated Medical Subject Headings [MeSH]
 

Adult, Aged, Blood Glucose, Blood Pressure, Body Mass Index, Diabetes Mellitus, Female, Glucose Tolerance Test, Humans, Lipids, Male, Middle Aged, Multivariate Analysis, Prospective Studies, ROC Curve, Risk Factors, Sex Factors, Type 2

 

Associated Logical Observation Identifiers Names and Codes [LOINC]
 

Parameter	LOINC's and Suggested Units
Age	21612-7 : yr      21612-7 : yr      21612-7 : years      30525-0 : Years old      30525-0 : yr      30525-0 : years
Height	8302-2 : cm      8301-4 : cm      3137-7 : cm      91370-7 : cm      3138-5 : cm      8306-3 : cm
Weight	29463-7 : kg      3141-9 : kg      8350-1 : kg      8351-9 : kg      79348-9 : kg      8335-2 : kg      75292-3 : kg      3142-7 : kg
FBS	76629-5 : mmol/L      1557-8 : mg/dL      1556-0 : mg/dL      41604-0 : mg/dL      14770-2 : mmol/L      77145-1 : mmol/L
Systolic Blood Pressure	8480-6 : mmHg
HDL Cholesterol	2085-9 : mg/dL      14646-4 : mmol/L
BMI	39156-5 : kg/m^2      59576-9 : kg/m^2      89270-3 : kg/m^2

 
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