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Multiple Organ Dysfunction Score (MODS)

 

Input
 

PaO2		Pascal cmH2O mmHg mm[Hg] torr
FIO2		%O2 % fractionO2 fraction litresO2
Central Venous Pressure		Pascal cmH2O mmHg mm[Hg] torr
Mean Arterial Pressure		Pascal cmH2O mmHg mm[Hg] torr
Heart Rate		/min beats/min bpm
Platelets		#/mcL #/microL / nl /mcL /microL /uL 10*3/uL 10*6/uL 10*6/uL 10E+9/L 10^3/microL K/mm3 K/uL Mill/mcl Million/ul Thous/mcL Thousand/uL X10E+09/L X10E+12/L cells/mcL cells/microL m/cmm thou/mcL x10(12)/L x10(3)/mcL x10(3)/microL x10(6)/L x10(6)/mcL x10(6)/microL x10(9)/L x1000/mm3 x10^12/L x10^3/mcL x10^3/microL x10^6/L x10^6/mcL x10^6/microL x10^9/L {cells}/uL
Bilirubin		mcmol/L mg% mg/dL
Creatinine		mcmol/L mg/dL mmol/L
Glasgow Coma Score		# count index logit none number points score

 
Results
 
Important: Inputs must be complete to perform calculation.

 

PaO2/FIO2		% fraction percent rate ratio
Pressure Adjusted Heart Rate		/min beats/min bpm
MODS Score		# count index logit none number points score
Decimal Precision   0 1 2 3

 

MODS Score

 

0 points:	ICU Mort 0%, Hosp Mort 0%, ICU Stay 2 Days
1 to 4 points:	ICU Mort 1-2%, Hosp Mort 7%, ICU Stay 3 Days
5 to 8 points:	ICU Mort 3-5%, Hosp Mort 16%, ICU Stay 6 Days
9 to 12 points:	ICU Mort 25%, Hosp Mort 50%, ICU Stay 10 Days
13 to 16 points:	ICU Mort 50%, Hosp Mort 70%, ICU Stay 17 Days
17 to 20 points:	ICU Mort 75%, Hosp Mort 82%, ICU Stay 21 Days
21 to 24 points:	ICU Mort 100%, Hosp Mort 100%

 

 

Data action

 
     
 
Include literature references: Yes   No

 

 

 

 
Equations used
 

PaO2/FIO2 = 100 * PaO2 / FIO2

Pressure Adjusted Heart Rate = HeartRate * CentralVenousPressure / MeanArterialPressure

MODSScore = PaO2/FIO2Factor + plateletsFactor + biliFactor + Pressure Adjusted Heart RateFactor + renalFactor + gcsFactor

 

 

Calculation Details and Variables

• PaO₂/FIO₂Factor is assigned values by this ordered logic:
  • If PaO₂/FIO₂ >300 PaO₂/FIO₂Factor = 0
  • Else if PaO₂/FIO₂ ≥226 PaO₂/FIO₂Factor = 1
  • Else if PaO₂/FIO₂ ≥151 PaO₂/FIO₂Factor = 2
  • Else if PaO₂/FIO₂ ≥76 PaO₂/FIO₂Factor = 3
  • Else PaO₂/FIO₂Factor = 4
• Pressure Adjusted Heart Rate Factor is assigned values by this ordered logic:
  • If Pressure Adjusted Heart Rate ≤10 Pressure Adjusted Heart Rate Factor = 0
  • Else if Pressure Adjusted Heart Rate ≤15 Pressure Adjusted Heart Rate Factor = 1
  • Else if Pressure Adjusted Heart Rate ≤20 Pressure Adjusted Heart Rate Factor = 2
  • Else if Pressure Adjusted Heart Rate ≤30 Pressure Adjusted Heart Rate Factor = 3
  • Else Pressure Adjusted Heart Rate Factor = 4
• plateletsFactor is assigned values by this ordered logic:
  • If Platelets >120 x10(3)/mcL, plateletsFactor = 0
  • Else if Platelets ≥81 x10(3)/mcL, plateletsFactor = 1
  • Else if Platelets ≥51 x10(3)/mcL, plateletsFactor = 2
  • Else if Platelets ≥21 x10(3)/mcL, plateletsFactor = 3
  • Else plateletsFactor = 4.
• biliFactor is assigned values by this ordered logic:
  • If Bilirubin ≤20 mcmol/L, biliFactor = 0
  • Else if Bilirubin <61 mcmol/L, biliFactor = 1
  • Else if Bilirubin <121 mcmol/L, biliFactor = 2
  • Else if Bilirubin ≤240 mcmol/L, biliFactor = 3
  • Else biliFactor = 4.
• renalFactor is assigned values by this ordered logic:
  • If Creatinine ≤100 mcmol/L, renalFactor = 0
  • Else if Creatinine <201 mcmol/L, renalFactor = 1
  • Else if Creatinine <351 mcmol/L, renalFactor = 2
  • Else if Creatinine ≤500 mcmol/L, renalFactor = 3
  • Else renalFactor = 4.
• gcsFactor is assigned values by this ordered logic:
  • If Glasgow Coma Score >14 points, gcsFactor = 0
  • Else if Glasgow Coma Score >12 points, gcsFactor = 1
  • Else if Glasgow Coma Score >9 points, gcsFactor = 2
  • Else if Glasgow Coma Score >6 points, gcsFactor = 3
  • Else gcsFactor = 4.

 

References

1. Marshall JC, Cook DJ, Christou NV, et al. Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med. 1995 Oct;23(10):1638-52. Review. PubMed ID: 7587228

 

Associated Medical Subject Headings [MeSH]
 

Humans,   Intensive Care Units,   Multiple Organ Failure,   Outcome Assessment (Health Care),   Predictive Value of Tests,   Prognosis,   Prospective Studies,   Reproducibility of Results,   Severity of Illness Index

 

Associated Logical Observation Identifiers Names and Codes [LOINC]
 

Parameter	LOINC's and Suggested Units
PaO2	11556-8 : mmHg      2703-7 : mmHg      19254-2 : mmHg
FIO2	3150-0 : %      19993-5 : %      19992-7 : %      19994-3 : %      19996-8 : %      19995-0 : %
Central Venous Pressure	60985-9 : mmHg      8591-0 : mmHg
Mean Arterial Pressure	8478-0 : mmHg      8458-2 : mmHg      76214-6 : mmHg      75996-9 : mmHg      76536-2 : mmHg
Heart Rate	8867-4 : beats/min      8893-0 : beats/min      8890-6 : beats/min      8889-8 : beats/min      68999-2 : beats/min      76282-3 : beats/min      69000-8 : beats/min      69001-6 : beats/min
Platelets	777-3 : x10^9/L      26515-7 : x10(3)/mcL
Bilirubin	1975-2 : mg/dL      32303-0 : mmol/L      59828-4 : mg/dL      54363-7 : mcmol/L      58941-6 : mg/dL
Creatinine	2160-0 : mg/dL      38483-4 : mg/dL      14682-9 : mcmol/L      22726-4 : mcmol/L      59826-8 : mcmol/L
Glasgow Coma Score	9269-2 : score      35088-4 : score

 
This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.