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  Sequential Organ Failure Assessment (Modified): mSOFA Score

 
Input
 
O2 Saturation  
FIO2  
Jaundice No (0)

Yes (3)
Blood Pressure Hypotension absent (0)

Mean arterial pressure <70 mmHg (1)

On Dopamine ≤5 mcg/kg/min or any Dobutamine (2)

On Dopamine >5 mcg/kg/min, Epinephrine <=0.1 mcg/kg/min or Norepinephrine <=0.1 mcg/kg/min (3)

On Dopamine >15 mcg/kg/min or Epinephrine >0.1 mcg/kg/min or Norepinephrine >0.1 mcg/kg/min (4)
Glasgow Coma Score  
Creatinine  

 
Results
 
 
O2 Saturation/FIO2  
mSOFA Score  
 

 
     
 
Include literature references: Yes   No

 
  mSOFA Score Interpretation

 
0 to 7 points: 4% Mortality
8 to 11 points: 31% Mortality
12 to 19 points: 58% Mortality

 
 

 
Equations used
 
O2 Saturation/FIO2 = 100 * O2 Saturation / FIO2
mSOFAScore = O2 Saturation/FIO2Factor + Jaundice + BloodPressure + GlasgowComaScoreFactor + CreatinineFactor

 
Calculation Details and Variables
  • Equation parameters such as Jaundice, have two or more discrete values that may be used in the calculation. The numbers in the parentheses, e.g. (0), represent the values that will be used.
  • GlasgowComaScoreFactor is assigned values by this ordered logic:
    • If Glasgow Coma Score <6 points GlasgowComaScoreFactor = 4
    • Else if Glasgow Coma Score ≤9 points GlasgowComaScoreFactor = 3
    • Else if Glasgow Coma Score ≤12 points GlasgowComaScoreFactor = 2
    • Else if Glasgow Coma Score ≤14 points GlasgowComaScoreFactor = 1
    • Else GlasgowComaScoreFactor = 0.
  • CreatinineFactor is assigned values by this ordered logic:
    • If Creatinine ≥5 mg/dL CreatinineFactor = 4
    • Else if Creatinine ≥3.5 mg/dL CreatinineFactor = 3
    • Else if Creatinine ≥2 mg/dL CreatinineFactor = 2
    • Else if Creatinine ≥1.2 mg/dL CreatinineFactor = 1
    • Else CreatinineFactor = 0.
  • safiFactor is assigned values by this ordered logic:
    • If O2 Saturation/FIO2 ≤150 safiFactor = 4
    • Else if O2 Saturation/FIO2 ≤235 safiFactor = 3
    • Else if O2 Saturation/FIO2 ≤315 safiFactor = 2
    • Else if O2 Saturation/FIO2 ≤400 safiFactor = 1
    • Else safiFactor = 0

 
References
  1. Grissom CK, Brown SM, Kuttler KG, et al. A modified sequential organ failure assessment score for critical care triage. Disaster Med Public Health Prep. 2010 Dec;4(4):277-84. PubMed ID: 21149228 PubMed Logo

 
Associated Logical Observation Identifiers Names and Codes [LOINC]
 
Parameter LOINC's and Suggested Units
O2Sat 2713-6 : %      51733-4 : %      59408-5 : %      
FIO2 3150-0 : %O2      19993-5 : %O2      19992-7 : %O2      19994-3 : %O2      19996-8 : %O2      19995-0 : %O2      
Glasgow Coma Score 35088-4 : score      55285-1 : score      9269-2 : score      
Creatinine 2160-0 : mg/dL      38483-4 : mg/dL      14682-9 : mcmol/L      22726-4 : mcmol/L      59826-8 : mcmol/L      

 
This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, and LOINC panels and forms file are copyright © 1995-2014, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and available at no cost under the license at http://loinc.org/terms-of-use.

 
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