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ROX Index (Respiratory rate--oxygenation)

 

Input
 

O2Sat		% fraction percent rate ratio
FIO2		%O2 % fractionO2 fraction litresO2
Respiratory Rate		br/min breaths/min

 
Result
 
Important: Inputs must be complete to perform calculation.

 

ROX Index		# count index logit none number points score
Decimal Precision   0 1 2 3

 

     
 
Include literature references: Yes   No

 

ROX Index Interpretation

 

>=4.88:	Reduced risk of intubation
>=3.85 and <4.88:	Indeterminant risk
<3.85:	Increased risk of intubation

 

 

 

 
Equations used
 

ROXIndex = O2Sat / (FIO2 / 100) / RespiratoryRate

 

 

References

1. Roca O, Messika J, Caralt B, et al. Predicting success of high-flow nasal cannula in pneumonia patients with hypoxemic respiratory failure: The utility of the ROX index. J Crit Care. 2016 Oct;35:200-5. PubMed ID: 27481760
2. Gianstefani A, Farina G, Salvatore V, et al. Role of ROX index in the first assessment of COVID-19 patients in the emergency department. Intern Emerg Med. 2021 Mar 1:1–7. PubMed ID: 33646507
3. Roca O, Caralt B, Messika J, Samper M, et al. An Index Combining Respiratory Rate and Oxygenation to Predict Outcome of Nasal High-Flow Therapy. Am J Respir Crit Care Med. 2019 Jun 1;199(11):1368-1376. PubMed ID: 30576221

 

Associated Medical Subject Headings [MeSH]
 

Adult,   Aged,   Artificial,   Blood Gas Analysis,   COVID-19,   Catheterization,   Cohort Studies,   Data Accuracy,   Diagnostic Techniques and Procedures,   Emergency Service,   Extracorporeal Membrane Oxygenation,   Female,   Hospital,   Humans,   Male,   Middle Aged,   Noninvasive Ventilation,   Nose,   Organ Dysfunction Scores,   Oximetry,   Oxygen,   Oxygen Inhalation Therapy,   Pneumonia,   Practice Guidelines as Topic,   Proportional Hazards Models,   Prospective Studies,   Respiration,   Respiratory Insufficiency,   Respiratory Rate,   Severity of Illness Index,   Treatment Failure

 

Associated Logical Observation Identifiers Names and Codes [LOINC]
 

Parameter	LOINC's and Suggested Units
O2Sat	2708-6 : %      2713-6 : %      51733-4 : %      59408-5 : %
FIO2	3150-0 : %      19993-5 : %      19992-7 : %      19994-3 : %      19996-8 : %      19995-0 : %
Respiratory Rate	9303-9 : breaths/min      9279-1 : breaths/min      76170-0 : breaths/min      19840-8 : breaths/min

 
This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, and LOINC panels and forms file are copyright © 1995-2014, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and available at no cost under the license at http://loinc.org/terms-of-use.