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  COVID-19 AID Score

Severe Hypoxia No (0)

Yes (1)

Important: Inputs must be complete to perform calculation.

Odds 7 Day  
Odds 14 Day  
Mortality 7 Day  
Mortality 14 Day  
Decimal Precision  

Include literature references: Yes   No

  • This calculator represents findings from the literature referenced below. It is important to understand that these findings may not be representative of the experience in your local healthcare system.
  • Severe Hypoxia is defined as requiring >4 L O2, non-rebreather mask, BiPAP, or intubation to maintain O2 saturation ≥90%, or failure to keep O2 saturation ≥90%
  • MAP: mean arterial pressure.

Equations used
Odds7Day = e((7.8913*ln(Age))+(-1.5434*ln(MAP))+(1.0738*KidneyFactor)+(0.9385*SevereHypoxia)-29.8233)
Odds14Day = e((6.4001*ln(Age))+(-1.2073*ln(MAP))+(1.0281*KidneyFactor)+(0.7977*SevereHypoxia)-24.17)
Mortality7Day = 100 * Odds7Day / (1 + Odds7Day)
Mortality14Day = 100 * Odds14Day / (1 + Odds14Day)


Calculation Details and Variables
  • KidneyFactor is assigned values by this ordered logic:
    • If Creatinine ≥2 mg/dL KidneyFactor = 1
    • Else KidneyFactor = 0.
  • Equation parameters such as Severe Hypoxia, have two or more discrete values that may be used in the calculation. The numbers in the parentheses, e.g. (0), represent the values that will be used.

  1. Hajifathalian K, Sharaiha RZ, Kumar S, et al. Development and external validation of a prediction risk model for short-term mortality among hospitalized U.S. COVID-19 patients: A proposal for the COVID-AID risk tool. PLoS One. 2020 Sep 30;15(9):e0239536. PubMed ID: 32997700 PubMed Logo

Associated Medical Subject Headings [MeSH]
         80 and over,   Aged,   Betacoronavirus,   COVID-19,   Coronavirus Infections,   Female,   Hospital Mortality,   Hospitalization,   Humans,   Logistic Models,   Male,   Massachusetts,   Middle Aged,   New York,   Pandemics,   Pneumonia,   ROC Curve,   Regression Analysis,   Retrospective Studies,   Risk Assessment,   Risk Factors,   SARS-CoV-2,   United States,   Viral

Associated Logical Observation Identifiers Names and Codes [LOINC]
Parameter LOINC's and Suggested Units
Age 21612-7 : yr      21612-7 : yr      21612-7 : years      30525-0 : Years old      30525-0 : yr      30525-0 : years      
MAP 8478-0 : mmHg      8458-2 : mmHg      76214-6 : mmHg      75996-9 : mmHg      76536-2 : mmHg      
Creatinine 2160-0 : mg/dL      38483-4 : mg/dL      14682-9 : mcmol/L      22726-4 : mcmol/L      59826-8 : mcmol/L      

This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, and LOINC panels and forms file are copyright © 1995-2014, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and available at no cost under the license at http://loinc.org/terms-of-use.


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