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COVID-19 Inflammation Score for Disease Severity

 

Input
 

Albumin		g/L g/dL gm/L gm/dL mg/L mg/dL
HS CRP		mg/L mg/L mg/dL nmol/L
WBC		#/mcL #/microL / nl /mcL /microL 10*3/uL 10*6/uL 10*6/uL 10E+9/L 10^3/microL K/mm3 K/uL Mill/mcl Million/ul Thous/mcL Thousand/uL X10E+09/L X10E+12/L cells/mcL cells/microL m/cmm thou/mcL x10(12)/L x10(3)/mcL x10(3)/microL x10(6)/L x10(6)/mcL x10(6)/microL x10(9)/L x1000/mm3 x10^12/L x10^3/mcL x10^3/microL x10^6/L x10^6/mcL x10^6/microL x10^9/L {cells}/uL

 
Result
 
Important: Inputs must be complete to perform calculation.

 

Inflammation Score		# count index logit none number points score

 

     
 
Include literature references: Yes   No

 

Inflammation Score Interpretation

 

0 points:	No significant inflammation; 1.1 to 1.8% in-hospital mortality
1 to 2 points:	Mild inflammation; 2.8 to 2.9% in-hospital mortality
3 to 4 points:	Moderate inflammation; 4.1 to 5.2% in-hospital mortality
5 to 6 points:	Severe inflammartion; 12.6 to 13.8% in-hospital mortality

 

 

 

Notes

• This calculator represents findings from the literature referenced below. It is important to understand that these findings may not be representative of the experience in your local healthcare system.
• Mortality estimates represent data from both derivation and validation cohorts.^[1]

 
Equations used
 

InflammationScore = AlbuminFactor + HSCRPFactor + WBCFactor

 

 

Calculation Details and Variables

• AlbuminFactor is assigned values by this ordered logic:
  • If Albumin ≤3.6 g/dL AlbuminFactor = 3
  • Else AlbuminFactor = 0.
• HSCRPFactor is assigned values by this ordered logic:
  • If HS CRP ≥13 mg/L HSCRPFactor = 2
  • Else HSCRPFactor = 0.
• WBCFactor is assigned values by this ordered logic:
  • If WBC ≥9.3 x10^3/microL WBCFactor = 1
  • Else WBCFactor = 0.

 

References

1. Gonzalez-Pacheco H, Bojalil R, Amezcua-Guerra LM, et al. Derivation and validation of a simple inflammation-based risk score system for predicting in-hospital mortality in acute coronary syndrome patients. J Cardiol. 2019 May;73(5):416-424. PubMed ID: 30600191

 

Associated Medical Subject Headings [MeSH]
 

Acute Coronary Syndrome,   Aged,   Biomarkers,   C-Reactive Protein,   Cohort Studies,   Female,   Hospital Mortality,   Humans,   Inflammation,   Leukocyte Count,   Male,   Middle Aged,   Odds Ratio,   Reproducibility of Results,   Risk Factors,   Serum Albumin

 

Associated Logical Observation Identifiers Names and Codes [LOINC]
 

Parameter	LOINC's and Suggested Units
Albumin	1751-7 : g/dL
HS CRP	1988-5 : mg/L      30522-7 : mg/L      71426-1 : mg/L      76486-0 : nmol/L
WBC	6690-2 : #/microL

 
This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, and LOINC panels and forms file are copyright © 1995-2014, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and available at no cost under the license at http://loinc.org/terms-of-use.