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  COVID-19 Inflammation Score for Disease Severity

 
Input
 
Albumin  
HS CRP  
WBC  

 
Result
 
 
Inflammation Score  
 

 
     
 
Include literature references: Yes   No

 
  Inflammation Score Interpretation

 
0 points: No significant inflammation; 1.1 to 1.8% in-hospital mortality
1 to 2 points: Mild inflammation; 2.8 to 2.9% in-hospital mortality
3 to 4 points: Moderate inflammation; 4.1 to 5.2% in-hospital mortality
5 to 6 points: Severe inflammartion; 12.6 to 13.8% in-hospital mortality

 
 
Notes
  • This calculator represents findings from the literature referenced below. It is important to understand that these findings may not be representative of the experience in your local healthcare system.
  • Mortality estimates represent data from both derivation and validation cohorts.[1]

 
Equations used
 
InflammationScore = AlbuminFactor + HSCRPFactor + WBCFactor

 

 
Calculation Details and Variables
  • AlbuminFactor is assigned values by this ordered logic:
    • If Albumin ≤3.6 g/dL AlbuminFactor = 3
    • Else AlbuminFactor = 0.
  • HSCRPFactor is assigned values by this ordered logic:
    • If HS CRP ≥13 mg/L HSCRPFactor = 2
    • Else HSCRPFactor = 0.
  • WBCFactor is assigned values by this ordered logic:
    • If WBC ≥9.3 x10^3/microL WBCFactor = 1
    • Else WBCFactor = 0.

 
References
  1. Gonzalez-Pacheco H, Bojalil R, Amezcua-Guerra LM, et al. Derivation and validation of a simple inflammation-based risk score system for predicting in-hospital mortality in acute coronary syndrome patients. J Cardiol. 2019 May;73(5):416-424. PubMed ID: 30600191 PubMed Logo

 
Associated Medical Subject Headings [MeSH]
 
         Acute Coronary Syndrome,   Aged,   Biomarkers,   C-Reactive Protein,   Cohort Studies,   Female,   Hospital Mortality,   Humans,   Inflammation,   Leukocyte Count,   Male,   Middle Aged,   Odds Ratio,   Reproducibility of Results,   Risk Factors,   Serum Albumin

 
Associated Logical Observation Identifiers Names and Codes [LOINC]
 
Parameter LOINC's and Suggested Units
Albumin 1751-7 : g/dL      
HS CRP 1988-5 : mg/L      30522-7 : mg/L      71426-1 : mg/L      76486-0 : nmol/L      
WBC 6690-2 : #/microL      

 
This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, and LOINC panels and forms file are copyright © 1995-2014, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and available at no cost under the license at http://loinc.org/terms-of-use.

 
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All information contained in and produced by the EBMcalc system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. Click here for full notice and disclaimer.
 
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