Cardiovascular Risk Assessment (10-year, MESA 2015, with or without CAC score)

Input

Race
Sex
Age
Total cholesterol
HDL cholesterol
Systolic blood pressure
On hypertension medication
On lipid-lowering medication
Diabetes
Smoker
Family history of MI
CAC

 

Results

Important: Inputs must be complete to perform calculation.
Terms
 
CV Risk MESA 2015
Terms CAC
 
CV Risk MESA 2015 CAC
Decimal Precision

 

Data action

     
 
Include literature references: Yes   No

Notes

  • MESA: Multi-Ethnic Study of Atherosclerosis; CAC: coronary artery calcification; HDL: high-density lipoprotein; MI: myocardial infarction; ASCVD: atherosclerotic cardiovascular disease; CHD: coronary heart disease.
  • This calculator helps predict the 10-year risk of the following ASCVD events:
    • CHD death
    • Nonfatal MI
    • Resuscitated cardiac arrest
    • Coronary revascularization in patient with angina
  • When a CAC score is known, a second 10-year risk calculation is done using independent hazard ratios associated with CAC scores.

Equations used


Terms = (Age * 0.0455) + (Sex * 0.7496) + ((Race == 1?1:0) * -0.2111) + ((Race == 2?1:0) * -0.5055) + ((Race == 3?1:0) * -0.19) + (Diabetes * 0.5168) + (Smoker * 0.4732) + (Totalcholesterol * 0.0053) - (HDLcholesterol * 0.0140) + (On lipid-lowering medication * 0.2473) + (Systolic blood pressure * 0.0085) + (On hypertension medication * 0.3381) + (Family history of MI * 0.4522)
 

CV Risk MESA 2015 = 100 * (1 - 0.99963e(Terms))
 

Terms CAC = (Age * 0.0172) + (Sex * 0.4079) + ((Race == 1?1:0) * 0.0353) + ((Race == 2?1:0) * -0.3475) + ((Race == 3?1:0) * -0.0222) + (Diabetes * 0.3892) + (Smoker * 0.3717) + (Totalcholesterol * 0.0043) - (HDLcholesterol * 0.0114) + (On lipid-lowering medication * 0.1206) + (Systolic blood pressure * 0.0066) + (On hypertension medication * 0.2278) + (Family history of MI * 0.3239) + (ln(CAC + 1) * 0.2743)
 

CV Risk MESA 2015CAC = 100 * (1 - 0.99833e(Terms CAC))
 

Calculation details and variables

  • Equation parameters such as Race, have two or more discrete values that may be used in the calculation. The numbers in the parentheses, e.g. (1), represent the values that will be used.

References

  1. Smith DA. ACP Journal Club. In adults without CVD, the MESA score, including coronary artery calcium, predicted 10-y risk for CHD events. Ann Intern Med. 2016 Mar 15;164(6):JC35. PubMed ID: 26974735 PubMedLink
  2. McClelland RL, Jorgensen NW, Budoff M, et al. 10-Year Coronary Heart Disease Risk Prediction Using Coronary Artery Calcium and Traditional Risk Factors: Derivation in the MESA (Multi-Ethnic Study of Atherosclerosis) With Validation in the HNR (Heinz Nixdorf Recall) Study and the DHS (Dallas Heart Study). J Am Coll Cardiol. 2015 Oct 13;66(15):1643-53. PubMed ID: 26449133 PubMedLink

Associated Medical Subject Headings [MeSH]


80 and over,   Aged,   Atherosclerosis,   Calcinosis,   Coronary Angiography,   Coronary Artery Disease,   Coronary Vessels,   Ethnic Groups,   Female,   Follow-Up Studies,   Humans,   Male,   Middle Aged,   Prospective Studies,   Reproducibility of Results,   Risk Assessment,   Risk Factors,   Tomography,   X-Ray Computed

Associated Logical Observation Identifiers Names and Codes [LOINC]

Parameter LOINC's and Suggested Units
Age 21612-7 : yr      21612-7 : yr      21612-7 : years      30525-0 : Years old      30525-0 : yr      30525-0 : years      
Total Cholesterol 2093-3 : mg/dL      14647-2 : mmol/L      
HDL Cholesterol 2085-9 : mg/dL      14646-4 : mmol/L      
Systolic Blood Pressure 8480-6 : mmHg      

 
This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.

Associated HCC ICD10-CM codes

Associated ICD9-CM codes

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