The EBMcalc module
Osmolal Gap Calculator is available in
EBMcalc Complete Edition.
This calculator yields the following results:
- Calculated Osm
- Osmolal Gap
Equation parameters include:
- Serum Na
- Serum Glucose
- Serum BUN
- Serum Ethanol
- EOF
- Measured Osm
References
- Bhagat CI, Garcia-Webb P, Fletcher E, et al. Calculated vs measured plasma osmolalities revisited. Clin Chem. 1984 Oct;30(10):1703-5. PubMed ID: 6537784
- Purssell RA, Pudek M, Brubacher J, et al. Derivation and validation of a formula to calculate the contribution of ethanol to the osmolal gap. Ann Emerg Med. 2001; 38:653. PubMed ID: 11719745
- Carstairs SD, Suchard JR, Smith T, et al. Contribution of serum ethanol concentration to the osmol gap: a prospective volunteer study. Clin Toxicol (Phila). 2013 Jun;51(5):398-401. PubMed ID: 23641935
- Liamis G, Filippatos TD, Liontos A, Elisaf MS. Serum osmolal gap in clinical practice: usefulness and limitations. Postgrad Med. 2017 May;129(4):456-459. PubMed ID: 28306366
- Lepeytre F, Ghannoum M, Ammann H, et al. Formulas for Calculated Osmolarity and Osmolal Gap: A Study of Diagnostic Accuracy. Am J Kidney Dis. 2017 Sep;70(3):347-356. PubMed ID: 28578820
- Nguyen MK, Song L, Kao L, et al. Is the Osmolal Concentration of Ethanol Greater Than Its Molar Concentration? Front Med (Lausanne). 2020 Jan 8;6:306. PubMed ID: 31970159
- Khajuria A, Krahn J. Osmolality revisited--deriving and validating the best formula for calculated osmolality. Clin Biochem. 2005 Jun;38(6):514-9. PubMed ID: 15885229
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