EBMcalc Logo
   INTRO    EQUATIONS    CRITERIA    DECISION    CONVERT    SPECIALTIES    REFS    SEARCH    NEW    FHIR APP    POLICIES    CONTACT
 
Osmolal Gap Calculator (SI units)

 
The EBMcalc module Osmolal Gap Calculator (SI units) is available in EBMcalc Complete Edition.
 

 
This calculator yields the following results:
 
Equation parameters include:
 
References
  1. Bhagat CI, Garcia-Webb P, Fletcher E, et al. Calculated vs measured plasma osmolalities revisited. Clin Chem. 1984 Oct;30(10):1703-5. PubMed ID: 6537784 PubMedLink
  2. Purssell RA, Pudek M, Brubacher J, et al. Derivation and validation of a formula to calculate the contribution of ethanol to the osmolal gap. Ann Emerg Med. 2001; 38:653. PubMed ID: 11719745 PubMedLink
  3. Carstairs SD, Suchard JR, Smith T, et al. Contribution of serum ethanol concentration to the osmol gap: a prospective volunteer study. Clin Toxicol (Phila). 2013 Jun;51(5):398-401. PubMed ID: 23641935 PubMedLink
  4. Liamis G, Filippatos TD, Liontos A, Elisaf MS. Serum osmolal gap in clinical practice: usefulness and limitations. Postgrad Med. 2017 May;129(4):456-459. PubMed ID: 28306366 PubMedLink
  5. Lepeytre F, Ghannoum M, Ammann H, et al. Formulas for Calculated Osmolarity and Osmolal Gap: A Study of Diagnostic Accuracy. Am J Kidney Dis. 2017 Sep;70(3):347-356. PubMed ID: 28578820 PubMedLink
  6. Nguyen MK, Song L, Kao L, et al. Is the Osmolal Concentration of Ethanol Greater Than Its Molar Concentration? Front Med (Lausanne). 2020 Jan 8;6:306. PubMed ID: 31970159 PubMedLink
  7. Khajuria A, Krahn J. Osmolality revisited--deriving and validating the best formula for calculated osmolality. Clin Biochem. 2005 Jun;38(6):514-9. PubMed ID: 15885229 PubMedLink

 

 

 
Legal Notices and Disclaimer

 
All information contained in and produced by the EBMcalc system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. EBMcalc is NOT a medical device. EBMcalc NEVER stores cookies or other persistent data in user's browsers. Click here for full notice and disclaimer.
 
EBMcalc is Copyright © 1998-2025 Foundation Internet    [Build 275671 v25.1]